Excellacor- The Original Systemic Formula
(Exclzyme- Same Exact Formula, New Name!)
A powerful systemic enzyme blend formulated to support normal fibrin metabolism, metabolic health, and joint, muscle and tissue health.*
Why Take Excellacor?
Excellacor is a potent blend of serrapeptase, proteases and herbs that supports metabolic health, including joint, muscle and tissue health, healthy circulation, and healthy fibrin metabolism.*
This powerful systemic blend supports:
- Overall Metabolic Health*
- Healthy Circulation*
- Muscle Recovery*
- Joint & Tendon Health*
- Vital Energy Levels*
- Healthy Stamina*
- Healthy Heels and Feet*
- Normal Circulation*
What’s Inside Excellacor
- Enteric-coated Serrapeptase (phthalate-free): a powerful fibrinolytic enzyme.*
- Bromelain: Proteolytic enzyme found in the pineapple plant; known for immune support.*
- Papain: Derived from papaya; supports the body’s natural immune response.*
- Lipase: Supports the breakdown of fats into essential fatty acids that are needed for healthy circulation.*
- Amylase: Breaks down carbohydrates and starches into simple sugars.*
- Rutin: Bioflavonoid that provides antioxidant support.*
- Amla: Natural source of Vitamin C, supports regulatory immune response.*
What Isn’t Inside Excellacor
Excellacor is free of pesticides, chemicals, preservatives, animal derivatives, dairy, yeast, fish or shellfish, peanuts, and tree nuts. All individual enzymes are kosher-certified ingredients, and suitable for vegetarians and vegans.
All products by AST Enzymes are manufactured in the USA from FDA registered facility that follows GMP guidelines.
What Sets Excellacor Apart
Excellacor contains AST’s original proprietary formula created by our master enzymologist. Originally marketed as Exclzyme, it has been commercially available for nearly 20 years. Its loyal use by companies, health practitioners and consumers have made it the #1 non-animal derived systemic formulation.
Excellacor has an enteric coating that allows the powerful enzyme blend to bypass the acidic environment of the stomach and reach the small intestine, where absorption occurs. Our enteric-coated serrapeptase has been formulated with the use of Methacrylic Acid Copolymer (MAAC), a safe food-grade compound used in the pharmaceutical industry with no reported side effects. Without enteric coating, enzymes will denature, or lose their effectiveness, in the stomach.
In addition, various proteases in Excellacor help break down proteins and amino acid chains, promoting total body support.*
Excellacor also supports healthy fibrin levels in the circulatory system.*
Fibrin is a protein that the body produces when healing. The protein precursor fibrinogen is converted into fibrin, which forms a layer of connective tissue inside the blood vessel. The fibrin strands assemble into a net-like structure over an affected vessel and harden, forming a “patch” to prevent further damage.
While fibrin is meant to have a protective function in the body, too much fibrin buildup can cause problems.
Why Choose Excellacor
Excellacor’s unique proprietary formula and efficacy-maximizing enteric coating make it the most potent blend on the market to support normal fibrin metabolism, metabolic health, and joint, muscle, and tissue health.*
Our enzymes are manufactured in a ISO 9001:2000 and GMP certified facilities, and undergo rigorous quality testing.
Everybody Needs a Healthy Body
of potentially toxic substances from the body is a crucial part in the
metabolic processes for optimal health. A variety of health issues can
develop if toxins within the body impair enzyme function or availability
or without a proper store of enzymes.
For instance, the immune
system can be overwhelmed with bacteria, fungi, toxins and even food
particles that don’t get completely digested in the gastro-intestinal
tract. In many instances, proteins created by these distresses found
within the body, which the body detects as foreign, can initiate an
immune response. Recognized as antigens, the immune system produces
antibodies to start the process of the proteins’ degradation and
removal. After coupling with one another, these antigens and antibodies
form circulating immune complexes (CICs), which induce attack and
destruction by the immune system’s macrophages (white blood cells
specifically designed to destroy CICs). This process is known as
inflammation – the body’s natural healing mechanism
In cases where
inflammation is prolonged or when CICs are predominant within the
body’s tissues and organs, the body may not have enough enzyme potential
to begin the next process of renewal and recovery. Moreover, research
has demonstrated that a lack of proteolytic enzymes may not cause an
inadequate response to a large accumulation of CIC’s in the body.
Excellacor® for Total Body Support
address this problem, Excellacor has been formulated with an ample supply
of various proteases to facilitate the body’s immune defenses and
breakdown free-roaming CICs that can keep the body in a constant state
Enteric-coated serrapeptase highlights this
powerful mix of proteolytic enzymes with its scientifically proven
fibrinolytic power (to learn more about enteric coating used in AST
Enzymes products, please click the "Compare" tab). Excellacor also
contains papain and bromelain, enzymes known for their potent systemic
In addition to these systemic and digestive proteases,
lipase and amylase also offer their own enzyme activity to bolster the
body with extra catalytic energy, especially for the complete digestion
of fats, sugar and protein complexes. And for extra synergy, Excellacor is
rounded with anti-oxidant support in the form of rutin and amla, herbs
well known for their unique bioflavanoid content, especially useful for
tissue rejuvenation and recovery.*The entire systemic enzyme blend is
manufactured in a ISO 9001:2000 and GMP certified facilities using our
Bioactive Protein Peptide System® (BPPS).
What is systemic enzyme therapy?
enzyme therapy refers to the therapeutic use of natural enzymes to
produce desired healing effects. Systemic enzymes are absorbed from the
small intestine where they enter the bloodstream and execute their
effects on the entire body as a system. Their crucial role in normal
inflammatory response assists and supports the body in accelerating
What is a systemic proteolytic enzyme?
enzymes break down proteins into their building-blocks, which are
called amino acids. Systemic proteolytic enzymes are responsible for
breaking down accumulated protein and waste substances found in the
circulatory system and connective tissue. Waste materials produced from
inflammation and other biochemical processes can build up, contributing
to excessive scarring and perpetuated immune responses. Excessive
scarring, particularly of the organs, can exacerbate symptoms of the
associated disease. The waste product of specific concern is known as
fibrin. Regular systemic proteolytic enzyme use can improve circulation
and aid in flushing out these waste products.
What is fibrin?
is a protein-based substance that is needed to help clot one’s blood,
playing a substantial role in immune response and healing. When the body
responds to injury or chronic inflammation, fibrin is recruited to the
damaged area to form scar tissue. Although the body is equipped with
plasmin, a naturally occurring enzyme responsible for breaking down
excess fibrin, some people are at a disadvantage – as aging occurs,
plasmin levels progressively decrease. This actually increases the risk
for excessive, undesirable scar tissue formation in the body.
Are systemic enzymes anti-inflammatory drugs?
systemic enzymes produce anti-inflammatory effects, they are not
considered a drug. Since enzymes are naturally occurring within the
body, systemic enzyme therapy is considered supplementation. One
difference between systemic enzymes and NSAIDs (Non-steroidal
anti-inflammatory drugs) involves the duration of action. While NSAIDs
produce short-term pain relief, systemic enzymes can produce long-term
alleviation with appropriate use.
largest difference between NSAIDS and systemic enzymes is the mechanism
of action and possible side effects. NSAIDs block the production of
prostaglandins, which are responsible for inflammation and swelling.
However, prostaglandins protect the lining of the stomach, and prolonged
use of NSAIDs can reduce this protection and increase the risk of
developing ulcers. Conversely, regular use of systemic enzymes has no
negative side effects and can actually provide protective effects
against excess inflammation.
Why is it important to take Excellacor on an empty stomach?
most absorption occurs in the small intestine, the systemic enzymes
must bypass the stomach to gain access there. If the enzymes are taken
with food, they will likely begin working to break down your food within
the stomach, rather than passing through to the small intestine. Taking
systemic enzymes like Excellacor with food will compromise their
absorption, as well as their effectiveness.
Does Excellacor have an enteric coating?
the serrapeptase in Excellacor is enterically coated. While similar
systemic enzymes may have the same active ingredients, most do not
utilize enteric coating. The purpose of enteric coating is to protect
the enzyme from the acidic environment of the stomach. High activity
level is preserved until the enzymes reach the small intestine, where
absorption into the bloodstream takes place. While the enteric coating
can withstand the acidic environment of the stomach, the alkaline
environment of the small intestine will disintegrate the enteric
coating, allowing the enzyme to be active within the bloodstream.
Do you use phthalates in your enteric coating?
our enteric coating does not use or contain phthalates. At AST Enzymes,
we use Methacrylic Acid Copolymer (MAAC) for our enteric coating.
Compared to other commonly used enteric coating agents such as Cellulose
Acetate Phthalate (CAP) and Hydroxypropyl Methycellulose Phthalate
(HPMCP), MAAC is the most gastro-resistant and does not carry the same
risks. Additionally, MAAC is considered GRAS (Generally Recognized as
Safe) by the FDA and is approved for use by the European Food Safety
Authority. To learn more about enteric coating used in AST Enzymes
products, please click the 'Compare" tab.
How long should I take Excellacor before feeling results?
people experience varying ailments and severity of disease, the length
of time to include systemic enzymes in your regimen may vary as well. As
an overall guideline, it is typically recommended that new systemic
enzyme users start off slow. A starter dose is generally one capsule,
three times daily. After three to four days of proven tolerance, the
dose can be increased to a therapeutic dose of 3 capsules, 3 times per
day. At this point, results may be monitored, and dosage should be
adjusted accordingly. Some consumers find their therapeutic dose between
9-15 capsules per day, while others only need 3-6. There are several
factors that may affect results and required dosage, including:
· Severity of symptoms
· Time of administration (Better absorbed on an empty stomach)
· Adherence to regimen
· Nutritional state
What if I miss a dose?
consistent use of systemic enzymes will provide the best results,
however missed doses of systemic enzymes do not have serious
repercussions. Although symptoms alleviated by systemic enzyme therapy
may resurface, getting back on track by remembering to take your next
dose will suffice. There is also the option of incorporating another
dose during the day. There is no need to “double up,” on one dose - and
remember, systemic enzymes are best absorbed on an empty stomach.
Are there any side effects involved with Excellacor?
use of Excellacor has not been shown to exhibit detrimental effects,
neither long term nor short term. Just as dosage requirements vary, side
effects may vary as well. Although gastrointestinal disturbances have
been reported by a small percentage of new users, tolerance is
maintained once the dosage is adjusted. Minor allergic reactions, like
reddening of the skin, are also rare occurrences, and can be seen with
extremely high doses. There are no known interactions with prescription
or over the counter drugs while using systemic enzyme therapy. However,
it is recommended that you consult with your physician about starting
systemic enzymes, especially if you are currently on blood-thinning
medications or if you are pregnant or nursing.
Can I take Excellacor with other systemic enzymes?
enzymes may be taken together, yielding desirable results, as long as
they are taken on an empty stomach. In fact, it is often recommended
that systemic enzymes be combined. Products like Excellacor and
Serrapetase often have synergistic effects when taken together. This
means that the separate products work together to produce advantageous
results. By combining and enhancing the activity of the enzymes, their
effects on the healing process are more attainable.
Can I take Excellacor with digestive enzymes?
digestive and systemic enzymes are not contraindicated in terms of
ingredients, they cannot be taken at the same time. The purpose of
digestive enzymes is to aid in digestion of specific foods, so taking
them with food is an obvious recommendation. Because systemic enzymes
require an empty stomach for maximum absorption, they must be taken
separately from digestive enzymes. There are no adverse interactions
between systemic and digestive enzymes, but they serve different
purposes and thus should be taken as directed for best results.
Inflammation and Fibrin
reality of inflammation is that it affects everyone, men and women
alike. However, along with nearly all other tissue and organs,
inflammation can affect reproductive tissue and organs particularly. For
instance, many women experience painful swelling of the breast as well
as uterine fibroids. In men, prostate health is a major concern.
Although inflammation in each case may manifest differently in both men
and women, inflammation has one thing in common: fibrin.
is an essential protein that is produced during inflammation. As a
blood clotting protein, the body utilizes fibrin to contain blood loss
and keep infection at bay after injury. It is the initial step in the
body’s attempts at recovery. However, when inflammation has become
prolonged, fibrin along with other proteins such as collagen can begin
to transform original tissue into a tough fibrous matrix. Differentiated
and sometimes sequestered apart from healthy tissue, this fibrous
matrix still has the biological markers of inflammation. Nutrients and
other building blocks are still needed for healthy and normal tissue.
and proteolytic enzyme research over the years suggests that fibroids
in women and swollen prostate glands in men are indications that the
body has not been able to get past inflammation. The resulting fibrous
tissue usually accumulates toxins that have not been adequately removed
by the body.
Serrapeptase Research: Anti-inflammatory Activity
nearly 40 years, serrapeptase has been at the heart of systemic enzyme
therapy. Systemic enzymes such as serrapeptase have been used for
optimal cell, tissue, organ and metabolic function. Likewise, companies,
health practitioners and consumers have turned to the original Excellacor formulation for their systemic enzyme therapy needs.
in India conducted a study to assess the response of serrapeptase in
patients with carpal tunnel syndrome (CTS). They wanted to determine if a
conservative, non-surgical approach would be beneficial. Twenty
patients with CTS were evaluated clinically after 6 weeks taking
serrapeptase. Sixty five percent showed significant clinical
improvement, which was supported by improvement in electrophysiological
parameters. No significant side effects were observed. The doctors
concluded that serrapeptase therapy may prove to be a useful alternative
A clinical evaluation of
serrapeptase was conducted to determine its efficacy in reducing
inflammation in patients with breast engorgement. Serrapeptase was noted
to be superior to placebo for improvement of breast pain, breast
swelling and induration and while 85.7% of the patients receiving
serrapeptase had "Moderate to Marked" improvement. No adverse reactions
were reported with the use of serrapeptase. The researchers conclude
that serrapeptase is a safe and effective method for the treatment of
Moving to another part of the
body, a study was conducted in men with amicrobial prostato-vesiculitis
(APV is a non-infectious inflammation of the prostate). The researchers
wanted to determine if treatment with nonsteroidal anti-inflammatory
(NSAIDS) drugs, including serrapeptase, could reduce inflammation and
swelling of the prostate. The doctors conclude that in APV patients, the
treatment with NSAIDS, including serrapeptase is an effective therapy,
producing multiple positive effects.3
Excellacor Benefits and Sports Nutrition
are energetic catalysts that push essential chemical reactions in the
body in the right direction. In its quest for internal balance, the body
always turns to enzymes for help. In this way, Excellacor helps get
inflamed tissue over the hump.
Excellacor’s superior proteolytic
action assists the body in removing those larger protein molecules from
damaged cells and tissues as well as the inflammatory response itself.
In helping breakdown these compounds, the impediments for sustaining
healthy cell and tissue growth are removed and the processes for
rejuvenation and recovery can move forward. These facets of Excellacor make it ideal for maintaining healthy tissue repair following strenuous
physical training and activity.
Sport- and exercise-related muscle
pain and inflammation brought on by strong physical tension, excessive
training, and heavy competition are decreased with “excellent results”
due to the specific activity of systemic enzymes on exercise-induced
inflammation.4 Taking systemic enzymes prior activity can
also provide protective benefits to athletes who are at risk of injury,
resulting in significantly reduced duration of injury symptoms and
related absences from training and work. Systemic enzyme support also
improves recovery from sprains, as well as shortens recovery from sport
injuries severe enough to require surgery.5,6
Enzyme Activity in Excellacor® Proprietary Blend
Enteric Coated Serrapeptase
by silkworms to digest and emerge from their silken cocoons; studied
extensively for more than 50 years; an excellent fibrinolytic (fibrin
digesting) and powerful anti-inflammatory enzyme*
(break-down) proteins like casein, steak, gelatin, soy, fish and other
plant and animal proteins to smaller chains of polypeptides (small
proteins) and amino acids for easier uptake throughout the body
A collective name for the proteolytic (protein-digesting) enzymes found in the pineapple plant (Ananas comosus);
known for its anti-inflammatory properties. A good substitute for
animal-based enzymes a good substitute for pepsin and trypsin for
Obtained from the latex of the fruit of the Papaya tree; used for centuries as an effective digestive aid*
down carbohydrates, or more specifically, starches, into smaller
dextrins and sugars; produced naturally by humans, microorganisms and
Catalyzes the break-down of fats into essential fatty acids needed for healthy tissues and cells*
Also known as Indian gooseberry (Emblica officinalis); a natural, efficacious antioxidant, and one of the richest sources of absorbable vitamin C
Bioflavonoid; strengthens and tones arteries and veins; provides antioxidant support against free-radicals and inflammation*
Panagariya A, Sharma AK. A preliminary trial of serratiopeptidase in
patients with carpal tunnel syndrome. J Assoc Physicians India. 2000
2. Kee WH, Tan SL, Lee V, Salmon YM. The
treatment of breast engorgement with Serrapeptase (Danzen): a randomised
double-blind controlled trial. Singapore Med J. 1989 Feb; 30(1):48-54.
Vicari E, La Vignera S, Battiato C, Arancio A. Treatment with
non-steroidal anti-inflammatory drugs in patients with amicrobial
chronic prostato-vesiculitis: transrectal ultrasound and seminal
findings[Article in Italian]. Minerva Urol Nefrol. 2005 Mar; 57(1):53-9.
Nouza K. Physical activity and immune system. Systemic enzyme therapy
in prevention and treatment. Medicina Sportiva Boh Slov. 1997;
5. Zuschlag JM. Prophylactic administration of
Wobenzym to reduce consequences of sports injuries in karate fighters.
MUCOS Pharma GmbH & Co, Dept. Clinical Research, Geretsried,
6. Kerkhoffs GM, Struijs PA, de Wit C, Rahlfs VW, Zwipp
H, van Dijk CN. A double blind, randomised, parallel group study on the
efficacy and safety of treating acute lateral ankle sprain with oral
hydrolytic enzymes. Br J Sports Med. 2004 Aug; 38(4):431–435.
Free of pesticides, chemicals, preservatives, animal
derivatives, dairy, lactose, yeast, fish or shellfish, peanuts, tree
nuts, artificial sweeteners and colors.
All individual enzymes and probiotics are kosher-certified, and suitable for vegetarians and vegans.
Bioactive Protein Peptide System (BPPS®) is a proprietary
manufacturing process featuring complementary bioactive peptides,
ensuring greater enzyme stability, absorption and bio-availability.
The products and the claims made about specific products on this site have not been evaluated by the United States Food and Drug Administration .
This product is not intended to diagnose, treat, cure, or prevent any disease or medical condition. Please consult a physician or medical practitioner before taking this or any dietary supplement. Women who are pregnant, nursing, or are planning on becoming pregnant should not take any supplements without consulting their physician first.
All material on this website is for informational purposes only. Nothing
contained on this website is intended to be used as a medical diagnosis
or treatment. It should not be used in place of the advice of your
physician or qualified healthcare provider.
Detailed Product Information
- Total body inflammation support
- Supports overall metabolic health
- Healthy blood circulation & cleansing
- Recovery from muscle soreness
- Joint and tendon health