Myomin: Aromatase Inhibitor for Estrogen-Dominant Disorders

The primary role of estrogen is the development of female sex characteristics. It is also an important hormone in childbearing women and in maintain bone strength. Estrogen also plays a role in cell activity. When estrogen is released, it passes directly into cells throughout the body, binds to receptors in the target cells, and initiates cell activity, determining how they will function for the rest of an individual's life. Because estrogen dictates important mechanisms such as protein production and cell division, it is vital to growth processes not just during puberty but in adult life. However, its role in signalling cells to divide and multiply can trigger and promote abnormal growth of estrogen-responsive tissues. Estrogen-dominant disorders such as endometriosis, cysts, fibroids and breast cancer result from this process. Treatment of these disorders, therefore, involves blocking the action of estrogen of the affected tissues.